1) Describe the role of each cofactor/coenzyme/prosthetic group involved in the reaction catalyzed by the pyruvate dehydrogenase complex.

1) Describe the role of each cofactor/coenzyme/prosthetic group involved in the reaction

catalyzed by the pyruvate dehydrogenase complex.

2) What type of chemical reaction is involved in the conversion of isocitrate to α-ketoglutarate?

Name and describe the role of any cofactors. What other reaction(s) of the citric acid cycle are

of this same type?